In fact, this is the photo that Serene first manipulated. E is for Enormous! I mean, look at the size of that moose and its antlers. I'd probably have a more scared look than THAT on my face.
Other things that start with E that make me laugh:
E is for the need for Emergency Rooms.
E is for Extraterrestrial, or E.T. for short.
E is for top-notch Educations.
E is for Ender's Game.
E is for Engineers.
E is for English and its multiplicities.
Is for for an Error's Error.
E is for a literal Escape key.
E is for how awesome an Etch-a-sketch gallery would be.
E is for the tricks that your Eyes can play on you.
E is for Evacuation plans.